Correction: Neuron-Specific HuR-Deficient Mice Spontaneously Develop Motor Neuron Disease
نویسندگان
چکیده
منابع مشابه
Motor Neuron Disease
Neurologists in the 19th century recognized that muscle weakness could be due to primary disorders of muscle or secondary to loss of neuromuscular integrity, as happens when peripheral nerves are cut or when motor neurons degenerate. Furthermore, it was observed that there are forms of motor neuron degeneration which selectively affect upper motor neurons or lower motor neurons. A combination o...
متن کاملAssessing motor neuron disease.
Hadjikoutis and Wiles draw attention to a number of circumstances in which the serum chloride and bicarbonate can be misleading. They do not mention that they will also be misleading if they are measured when hypercapnia is increasing or decreasing. An exacerbation of hypercapnia will take 4 – 6 days to raise the serum bicarbonate and lower the serum chloride to new steady levels. 1 How long it...
متن کاملMotor neuron disease
Motor neuron disease (MND) represents one ofthe major unsolved problems in neurology. The literature is characterized by numerous speculative theories, mostly derived by analogy with other recognized causes of motor neuron death such as poliomyelitis, or from toxic exposures such as lead poisoning. However, analogous reasoning of this type has not, so far, given insights into MND itself, or res...
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Spinal muscular atrophy (SMA) is attributed to mutations in the SMN1 gene, leading to loss of spinal cord motor neurons. The neurotropic Sindbis virus vector system was used to investigate a role for the survival motor neuron (SMN) protein in regulating neuronal apoptosis. Here we show that SMN protects primary neurons and differentiated neuron-like stem cells, but not cultured cell lines from ...
متن کاملPain in motor neuron disease.
Twenty-seven of 42 patients with motor neuron disease had significant pain. The nature and duration of the pain are described along with an illustrative case-report. The aetiology and most effective treatment of this common complication of motor neuron disease remain unclear.
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2018
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1800930